Sorry for the long title.
This past Tuesday Microsoft released a slew of new security patches. I won't go into detail about all of them, but suffice it to say we're seeing KB979909 become a pretty hairy thorn in our side.
We deploy all of our updates via SCCM. In my pilot testing I've noticed quite a few machines that come up with an error code of -2147023293 with a HexErrorCode of 80070643. This error basically means a fatal error during installation.
Microsoft's recommendation on how to fix this is referenced here: http://support.microsoft.com/kb/923100/ however what I'm seeing in my environment is nearly a 10% failure rate on my pilot users. There's no real easy way to fix this remotely, and my help desk will be busy for a couple of days fixing this issue for the amount of calls they'll be receiving.
Other people are seeing the same problems. For the time being, we're pulling the update until we see a better solution than uninstall all versions of .NET as the fix.
Below are links to other people experiencing the same problem with this update. Some are also seeing problems with KB982168, and KB979906.
http://www.experts-exchange.com/OS/Microsoft_Operating_Systems/Q_26246663.html
If you're having the same problem, post a comment below.